Deletion of a disease resistance nucleotide-binding-site leucine-rich- repeat-like sequence is associated with the loss of the Phytophthora resistance gene Rps4 in soybean.
Identifieur interne : 002349 ( Main/Exploration ); précédent : 002348; suivant : 002350Deletion of a disease resistance nucleotide-binding-site leucine-rich- repeat-like sequence is associated with the loss of the Phytophthora resistance gene Rps4 in soybean.
Auteurs : Devinder Sandhu [États-Unis] ; Hongyu Gao ; Silvia Cianzio ; Madan K. BhattacharyyaSource :
- Genetics [ 0016-6731 ] ; 2004.
Descripteurs français
- KwdFr :
- MESH :
- génétique : Protéines végétales, Soja.
- métabolisme : Protéines végétales, Soja.
- pathogénicité : Phytophthora.
- Cartographie physique de chromosome, Haplotypes, Structure tertiaire des protéines.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : Plant Proteins.
- chemical , metabolism : Plant Proteins.
- genetics : Soybeans.
- metabolism : Soybeans.
- pathogenicity : Phytophthora.
- Haplotypes, Physical Chromosome Mapping, Protein Structure, Tertiary.
Abstract
Resistance of soybean against the oomycete pathogen Phytophthora sojae is conferred by a series of Rps genes. We have characterized a disease resistance gene-like sequence NBSRps4/6 that was introgressed into soybean lines along with Rps4 or Rps6. High-resolution genetic mapping established that NBSRps4/6 cosegregates with Rps4. Two mutants, M1 and M2, showing rearrangements in the NBSRps4/6 region were identified from analyses of 82 F(1)'s and 201 selfed HARO4272 plants containing Rps4. Fingerprints of these mutants are identical to those of HARO4272 for 176 SSR markers representing the whole genome except the NBSRps4/6 region. Both mutants showed a gain of race specificities, distinct from the one encoded by Rps4. To investigate the possible mechanism of gain of Phytophthora resistance in M1, the novel race specificity was mapped. Surprisingly, the gene encoding this resistance mapped to the Rps3 region, indicating that this gene could be either allelic or linked to Rps3. Recombinant analyses have shown that deletion of NBSRps4/6 in M1 is associated with the loss of Rps4 function. The NBSRps4/6 sequence is highly transcribed in etiolated hypocotyls expressing the Phytophthora resistance. It is most likely that a copy of the NBSRps4/6 sequence is the Rps4 gene. Possible mechanisms of the deletion in the NBSRps4/6 region and introgression of two unlinked Rps genes into Harosoy are discussed.
DOI: 10.1534/genetics.104.032037
PubMed: 15611183
PubMed Central: PMC1448712
Affiliations:
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Bhattacharyya</name></author></analytic><series><title level="j">Genetics</title><idno type="ISSN">0016-6731</idno><imprint><date when="2004" type="published">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Haplotypes (MeSH)</term><term>Physical Chromosome Mapping (MeSH)</term><term>Phytophthora (pathogenicity)</term><term>Plant Proteins (genetics)</term><term>Plant Proteins (metabolism)</term><term>Protein Structure, Tertiary (MeSH)</term><term>Soybeans (genetics)</term><term>Soybeans (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Cartographie physique de chromosome (MeSH)</term><term>Haplotypes (MeSH)</term><term>Phytophthora (pathogénicité)</term><term>Protéines végétales (génétique)</term><term>Protéines végétales (métabolisme)</term><term>Soja (génétique)</term><term>Soja (métabolisme)</term><term>Structure tertiaire des protéines (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Plant Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Plant Proteins</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Soybeans</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Protéines végétales</term><term>Soja</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Soybeans</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Protéines végétales</term><term>Soja</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Phytophthora</term></keywords><keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Phytophthora</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Haplotypes</term><term>Physical Chromosome Mapping</term><term>Protein Structure, Tertiary</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Cartographie physique de chromosome</term><term>Haplotypes</term><term>Structure tertiaire des protéines</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Resistance of soybean against the oomycete pathogen Phytophthora sojae is conferred by a series of Rps genes. We have characterized a disease resistance gene-like sequence NBSRps4/6 that was introgressed into soybean lines along with Rps4 or Rps6. High-resolution genetic mapping established that NBSRps4/6 cosegregates with Rps4. Two mutants, M1 and M2, showing rearrangements in the NBSRps4/6 region were identified from analyses of 82 F(1)'s and 201 selfed HARO4272 plants containing Rps4. Fingerprints of these mutants are identical to those of HARO4272 for 176 SSR markers representing the whole genome except the NBSRps4/6 region. Both mutants showed a gain of race specificities, distinct from the one encoded by Rps4. To investigate the possible mechanism of gain of Phytophthora resistance in M1, the novel race specificity was mapped. Surprisingly, the gene encoding this resistance mapped to the Rps3 region, indicating that this gene could be either allelic or linked to Rps3. Recombinant analyses have shown that deletion of NBSRps4/6 in M1 is associated with the loss of Rps4 function. The NBSRps4/6 sequence is highly transcribed in etiolated hypocotyls expressing the Phytophthora resistance. It is most likely that a copy of the NBSRps4/6 sequence is the Rps4 gene. Possible mechanisms of the deletion in the NBSRps4/6 region and introgression of two unlinked Rps genes into Harosoy are discussed.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">15611183</PMID><DateCompleted><Year>2005</Year><Month>06</Month><Day>21</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0016-6731</ISSN><JournalIssue CitedMedium="Print"><Volume>168</Volume><Issue>4</Issue><PubDate><Year>2004</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Genetics</Title><ISOAbbreviation>Genetics</ISOAbbreviation></Journal><ArticleTitle>Deletion of a disease resistance nucleotide-binding-site leucine-rich- repeat-like sequence is associated with the loss of the Phytophthora resistance gene Rps4 in soybean.</ArticleTitle><Pagination><MedlinePgn>2157-67</MedlinePgn></Pagination><Abstract><AbstractText>Resistance of soybean against the oomycete pathogen Phytophthora sojae is conferred by a series of Rps genes. We have characterized a disease resistance gene-like sequence NBSRps4/6 that was introgressed into soybean lines along with Rps4 or Rps6. High-resolution genetic mapping established that NBSRps4/6 cosegregates with Rps4. Two mutants, M1 and M2, showing rearrangements in the NBSRps4/6 region were identified from analyses of 82 F(1)'s and 201 selfed HARO4272 plants containing Rps4. Fingerprints of these mutants are identical to those of HARO4272 for 176 SSR markers representing the whole genome except the NBSRps4/6 region. Both mutants showed a gain of race specificities, distinct from the one encoded by Rps4. To investigate the possible mechanism of gain of Phytophthora resistance in M1, the novel race specificity was mapped. Surprisingly, the gene encoding this resistance mapped to the Rps3 region, indicating that this gene could be either allelic or linked to Rps3. Recombinant analyses have shown that deletion of NBSRps4/6 in M1 is associated with the loss of Rps4 function. The NBSRps4/6 sequence is highly transcribed in etiolated hypocotyls expressing the Phytophthora resistance. It is most likely that a copy of the NBSRps4/6 sequence is the Rps4 gene. Possible mechanisms of the deletion in the NBSRps4/6 region and introgression of two unlinked Rps genes into Harosoy are discussed.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Sandhu</LastName><ForeName>Devinder</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Agronomy, Iowa State University, Ames, Iowa 50011-1010, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gao</LastName><ForeName>Hongyu</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Cianzio</LastName><ForeName>Silvia</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Bhattacharyya</LastName><ForeName>Madan K</ForeName><Initials>MK</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Genetics</MedlineTA><NlmUniqueID>0374636</NlmUniqueID><ISSNLinking>0016-6731</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010940">Plant Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C097421">rps4 protein, plant</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D006239" MajorTopicYN="N">Haplotypes</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020161" MajorTopicYN="N">Physical Chromosome Mapping</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010838" MajorTopicYN="N">Phytophthora</DescriptorName><QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010940" MajorTopicYN="N">Plant Proteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017434" MajorTopicYN="N">Protein Structure, Tertiary</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013025" MajorTopicYN="N">Soybeans</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2004</Year><Month>12</Month><Day>22</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2005</Year><Month>6</Month><Day>23</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate 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1;88(21):9828-32</Citation><ArticleIdList><ArticleId IdType="pubmed">1682921</ArticleId></ArticleIdList></Reference><Reference><Citation>Genome Res. 2002 Sep;12(9):1305-15</Citation><ArticleIdList><ArticleId IdType="pubmed">12213767</ArticleId></ArticleIdList></Reference><Reference><Citation>Theor Appl Genet. 1992 May;83(8):1035-43</Citation><ArticleIdList><ArticleId IdType="pubmed">24202932</ArticleId></ArticleIdList></Reference><Reference><Citation>Genetics. 2004 Jan;166(1):493-503</Citation><ArticleIdList><ArticleId IdType="pubmed">15020438</ArticleId></ArticleIdList></Reference><Reference><Citation>Genomics. 1987 Oct;1(2):174-81</Citation><ArticleIdList><ArticleId IdType="pubmed">3692487</ArticleId></ArticleIdList></Reference><Reference><Citation>Theor Appl Genet. 2004 Jun;109(1):122-8</Citation><ArticleIdList><ArticleId IdType="pubmed">14991109</ArticleId></ArticleIdList></Reference><Reference><Citation>Anal Biochem. 1983 Jul 1;132(1):6-13</Citation><ArticleIdList><ArticleId IdType="pubmed">6312838</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2001 Jun 14;411(6839):826-33</Citation><ArticleIdList><ArticleId IdType="pubmed">11459065</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Plant Biol. 2003;54:23-61</Citation><ArticleIdList><ArticleId IdType="pubmed">14502984</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell. 2000 May;12(5):663-76</Citation><ArticleIdList><ArticleId IdType="pubmed">10810142</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Phytopathol. 2001;39:285-312</Citation><ArticleIdList><ArticleId IdType="pubmed">11701867</ArticleId></ArticleIdList></Reference><Reference><Citation>Theor Appl Genet. 2003 Feb;106(3):445-53</Citation><ArticleIdList><ArticleId IdType="pubmed">12589544</ArticleId></ArticleIdList></Reference><Reference><Citation>Gene. 1990 Aug 16;92(1-2):1-248</Citation><ArticleIdList><ArticleId IdType="pubmed">2172084</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell. 1999 Jul;11(7):1365-76</Citation><ArticleIdList><ArticleId IdType="pubmed">10402435</ArticleId></ArticleIdList></Reference><Reference><Citation>Plant Cell. 1998 Nov;10(11):1861-74</Citation><ArticleIdList><ArticleId IdType="pubmed">9811794</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Iowa</li></region><settlement><li>Ames (Iowa)</li></settlement><orgName><li>Université d'État de l'Iowa</li></orgName></list><tree><noCountry><name sortKey="Bhattacharyya, Madan K" sort="Bhattacharyya, Madan K" uniqKey="Bhattacharyya M" first="Madan K" last="Bhattacharyya">Madan K. Bhattacharyya</name><name sortKey="Cianzio, Silvia" sort="Cianzio, Silvia" uniqKey="Cianzio S" first="Silvia" last="Cianzio">Silvia Cianzio</name><name sortKey="Gao, Hongyu" sort="Gao, Hongyu" uniqKey="Gao H" first="Hongyu" last="Gao">Hongyu Gao</name></noCountry><country name="États-Unis"><region name="Iowa"><name sortKey="Sandhu, Devinder" sort="Sandhu, Devinder" uniqKey="Sandhu D" first="Devinder" last="Sandhu">Devinder Sandhu</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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